4- Chloro-benzoic acid is an organic compound with the chemical formula ClC6H4CO2H. This organic compound is a mono chloro-benzoic acid that carries a chloro-substituent at position 4. It is the conjugate acid of 4- chloro-benzoates and is derived from benzoic acid.
This compound is produced by the oxidation of 4-chlorotoluene.
physical and chemical properties:
4 -Chloro-benzoic acid appears as triclinic crystals or light fluffy white powder and is soluble in some organic solvents.
It is also incompatible with strong oxidizing agents and strong bases.
The most important physical and chemical properties of this compound can be summarized in the following table:
|Molar mass||156.57 g·mol−1|
|P ka||3.98 (at 25 °C)|
|Melting Point||241.5 °C (466.7 °F; 514.6 K)|
|Boiling point||276 °C (529 °F; 549 K)|
|Solubility in water||In water, 77 mg/L at 25 °C|
Soluble in 5290 parts water
|Solubility||Insoluble in benzene, carbon tetrachloride;|
very soluble in ethanol;
slightly soluble in ethyl ether, chloroform
Freely soluble in alcohol, ether
|vapor pressure||0.3Pa at 25 °C|
|Flashpoint||238 °C (460 °F)|
|Other names||p-Chloro- benzoic acid|
para-Chloro- benzoic acid
|Chemical Structure Depiction|
Formula and structure of 4-chloro benzoic acid:
The structure of this compound with the chemical formula ClC6H4CO2H includes the arrangement of atoms and the chemical bonds that hold the atoms together. This organic molecule includes a six-membered ring, a carboxylic acid, and a hydroxyl group.
These compounds are benzoic acids that carry the halogen atom on the benzene ring.
4-chloro benzoic acid production process:
-For the preparation of p-chloro-benzoic acid from a mixture of ortho and parachlorotoluene, which involves the oxidation of this mixture using oxygen-containing gas in a reaction medium consisting of monocarboxylic acid.
Applications and uses of 4-chloro-benzoic acid:
- p-Chloro-benzoic acid can be prepared by reacting p-aminobenzoic acid.
- Preparation by catalytic oxidation of 1-chloro-4-ethylbenzene
- Produced by oxidation of p-chlorobenzaldehyde.
- this compound prevents the growth of fungi, yeasts, and some bacteria. It is used as a pH regulator and preservative in food and the growth of microbes is used to keep food safe.
- Used as agrochemical in agriculture to repel pests and insects.
As a laboratory reagent in the manufacture of chemicals.
- The sodium salt of p-Chloro-benzoic acid is used as a preservative.
- preservative for adhesives and paints.
- Involved as a bacterial xenobiotic metabolite.
- 4- chloro-benzoic acids are also used in the manufacture of medicines.
Safety information of 4-chloro-benzoic acid:
Symptoms of exposure to this compound include eye and skin irritation.
This compound may be harmful by inhalation, ingestion, or absorption into the skin.
Irritating to eyes, skin, mucous membranes, and upper respiratory tract.
Skin Contact: Immediately flush skin with water.
Inhalation: move the person to the fresh air.
Eye Contact: Rinse eyes with water for several minutes.
Ingestion: Rinse mouth. Do not induce vomiting.
Packing and storage:
Keep the container tightly closed in a dry and well-ventilated place.