Ferric Citrate

Ferric citrate is an ionic chemical compound with formula Fe (C6H5O7). It used to control phosphorus levels in adults with chronic kidney disease who are on dialysis. Iron(III) citrate contains iron that binds to the phosphates you take in through food, which helps your body absorb fewer phosphates. This can lower the amount of phosphorus (a mineral) in your blood. A method for preparing ferrous citrate having the empirical formula C H O Fe which comprises mixing citric acid with an aqueous solution of a ferrous salt taken from the group consisting of ferrous sulfate, ferrous acetate, ferrous ammonium sulfate, and ferrous propionate, boiling the solution under reflux conditions for a sufficient time to form and precipitate ferrous citrate while maintaining the pH between 2 and 4 and separating the precipitate from the solution. Iron citrate is a prescription medication used to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis. It is also used to treat iron-deficiency anemia in patients with chronic kidney disease (CKD), not on dialysis. Ferric Citrate belongs to a group of drugs called ferric iron-based phosphate binders. These work by binding to phosphate in the body to pass it through the digestive system and eliminate the phosphate through the stool. In addition, ferric citrate can help replenish iron in the body necessary to make healthy red blood cells. This medication comes in tablet form and is taken typically 3 times a day, with meals. Common side effects of Ferric Citrate include diarrhea, discolored (dark) stools, nausea, constipation, and vomiting.

Physical and Chemical Properties 

In the table below some of the chemical and physical properties of this product are mentioned. All data that is mentioned in this table is gathered from Wikipedia website:

Applications of Ferrous Citrate

Iron(III) citrate and Ferric Citrate can be used as a dietary supplement and as a nutrient. Iron has a vital function in combining with protein and copper to make hemoglobin. Iron also prevents fatigue and promotes good skin tone.

Ferric citrate may also be used for purposes not listed in this medication guide.

Keep this medicine out of the reach of children. An accidental overdose of Iron citrate by a child can be fatal.

You should not use ferric citrate if you are allergic to it, or if you have:

Iron overload disorder (hemochromatosis).

To make sure ferric citrate is safe for you, tell your doctor if you have:

1.Liver disease;

2. A stomach or intestinal disorder

3. A history of stomach bleeding

4. If you have recently had stomach or intestinal surgery or

5. If you take thyroid replacement medicine (levothyroxine, Synthroid, and others).

It is not known whether this medicine will harm an unborn baby. An overdose of iron can cause miscarriage, birth defects, or pregnancy-related diabetes. Tell your doctor if you are pregnant or plan to become pregnant while taking this medicine.

It is not known whether ferric citrate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Your dose needs may be different during pregnancy or while you are nursing.

This medicine is not approved for use by anyone younger than 18 years old.

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